Oct4, Sox2, Klf4, and Nanog are transcription factors that act as triggers to induce somatic cells to become pluripotent stem cells. Oct4, Sox2, Klf4, and Nanog are all crucial components of stem cells and have a significant impact on biological operations.
An activator protein, which is necessary for transcription to occur when it is under positive control, binds to the DNA. transcription is put under negative control when a protein called a repressor binds to the DNA and prevents transcription. Positive gene regulation involves the transcription of genes, whereas negative gene regulation typically prevents the expression of genes. This is the primary distinction between positive and negative gene regulation.
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