microRNA controls gene expression mainly by binding with messenger RNA (mRNA) in the cell cytoplasm. miRNAs act as post-transcriptional regulators of their messenger RNA (mRNA) targets via mRNA degradation and/or translational repression.
How does miRNA affect gene expression?
- When miRNA attaches to complementary mRNA regions, it forms a RISC complex, preventing translation, which prevents the final protein product from being made. By blocking translation and preventing protein synthesis, miRNA binding and inhibition affect how proteins are made.
- By base-pairing with the target mRNA to inhibit its production, the miRNA acts as a guide. Which silencing mechanism will be used cleavage of the target messenger RNA (mRNA) with subsequent destruction or translation inhibition depends on how complementary the guide and mRNA target are to one another.
Learn more about miRNA here: brainly.com/question/14136087
#SPJ4
