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Where in the body does a mutation have to occur in order to cause an inherited change in the offspring?

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Answer

This has to be in  germinal cells./germ-line cells.That is in the sex cells of either sperms or the eggs. it may occur during Gametogensis.

The fusions of these sex cells  resulted in a new organism.Where the genes inherited  in the two  sex cells are fully expressed,It is duding the expression that the effect of the mutation will be shown.

Explanation: